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Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

Abstract:

Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed countries. We conducted a multi-stage genome-wide association study for PrCa and previously reported the results of the first two stages, which identified 16 PrCa susceptibility loci. We report here the results of stage 3, in which we evaluated 1,536 SNPs in 4,574 individuals with prostate cancer (cases) and 4,164 controls. We followed up ten new association signals through genotyping in 51,311 samples in 30 stud...

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Publisher copy:
10.1038/ng.882

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Journal:
Nature Genetics
Volume:
43
Issue:
8
Pages:
785-791
Publication date:
2011-08-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:311db911-fc6e-4d09-9b2b-3ca75a96a6b0
Source identifiers:
172475
Local pid:
pubs:172475
Language:
English

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