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Journal article

Common allelic variants of exons 10, 12, and 33 of the thyroglobulin gene are not associated with autoimmune thyroid disease in the United Kingdom.

Abstract:

Thyroglobulin (Tg) is a major autoantigen for autoimmune thyroid disease (AITD). The Tg gene (Tg) has been mapped to chromosome 8q24, which has recently been linked in two independent studies to AITD. Association of specific alleles of microsatellite markers within Tg itself supports a role for Tg as a good candidate susceptibility locus for AITD. Resequencing of the Tg exons has led to the identification of a number of novel single nucleotide polymorphisms, four of which have been reported t...

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Publisher copy:
10.1210/jc.2004-1336

Authors


Collins, JE More by this author
Heward, JM More by this author
Howson, JM More by this author
Carr-Smith, J More by this author
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Journal:
The Journal of clinical endocrinology and metabolism
Volume:
89
Issue:
12
Pages:
6336-6339
Publication date:
2004-12-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:30eaf118-6937-4a00-ae9b-bddbb6348025
Source identifiers:
176265
Local pid:
pubs:176265

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