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Journal article

Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis.

Abstract:

Loss of heterozygosity affecting chromosome 7q is common in acute myeloid leukemia and myelodysplastic syndromes, pointing toward the essential role of this region in disease phenotype and clonal evolution. The higher resolution offered by recently developed genomic platforms may be used to establish more precise clinical correlations and identify specific target genes. We analyzed a series of patients with myeloid disorders using recent genomic technologies (1458 by single-nucleotide polymor...

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Publication status:
Published

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Journal:
Blood
Volume:
119
Issue:
25
Pages:
6109-6117
Publication date:
2012-06-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:30d9806f-3bd7-4d43-92b4-b54a2b6111f9
Source identifiers:
329110
Local pid:
pubs:329110

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