Journal article icon

Journal article

Human keratinocyte induction of rapid effector function in antigen-specific memory CD4+ and CD8+ T cells.

Abstract:

The ability of human keratinocytes to present antigen to T cells is controversial and, indeed, it has been suggested that keratinocytes may promote T cell hyporesponsiveness. Furthermore, it is unclear whether keratinocytes can process antigen prior to MHC class I and class II presentation. We tested the ability of keratinocytes to induce functional responses in epitope-specific CD4+ and CD8+ memory T cells using peptides, protein and recombinant expression vectors as sources of antigen. Kera...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/eji.200636915

Authors


Ardern-Jones, MR More by this author
Kasprowicz, V More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, Experimental Medicine Division
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Expand authors...
Journal:
European journal of immunology
Volume:
37
Issue:
6
Pages:
1485-1493
Publication date:
2007-06-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:30ad3631-edc9-42d5-bd4e-9f510e683dfa
Source identifiers:
10474
Local pid:
pubs:10474

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP