Dataset
Human RECQL5 Helicase; A Target Enabling Package
- Version:
- 3
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(pdf, 966.7KB)
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Authors/Creators
Contributors
+ Newman, J
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Genomics Consortium
Role:
Researcher
+ Aitkenhead, H
Institution:
University of Oxford
Oxford college:
Balliol College
Role:
Researcher
+ Savitsky, P
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Genomics Consortium
Role:
Researcher
Funding
Bibliographic Details
- Publisher:
- University of Oxford
- Publication date:
- 2018
- Version number:
- 3
Item Description
- Keywords:
- Subjects:
- Documentation:
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A description of the materials and methods is included within the TEP datasheet. RECQL5 is a member of the RecQ family of helicase which have important functions in DNA repair pathways and maintenance of genome integrity. RECQL5 has recently been identified as a synthetic lethal candidate in various haematological malignancies and has been verified by knockdown to sensitize myeloproliferative neoplasms (MPN) to DNA damaging agents. In this TEP we have expressed purified and determined the fir... Expand documentation
- UUID:
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uuid:308b8d6e-c67b-4c25-b9fb-226efbe8c479
- Deposit date:
- 2018-05-08
Related Items
Terms of use
- Copyright date:
- 2018
- Licence:
- ORA Terms and conditions
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