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Journal article

Approximate statistics of gapped alignments.

Abstract:

A heuristic approximation to the score distribution of gapped alignments in the logarithmic domain is presented. The method applies to comparisons between random, unrelated protein sequences, using standard score matrices and arbitrary gap penalties. It is shown that gapped alignment behavior is essentially governed by a single parameter, alpha, depending on the penalty scheme and sequence composition. This treatment also predicts the position of the transition point between logarithmic and l...

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Publication status:
Published

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Publisher copy:
10.1089/cmb.1999.6.91

Authors


Publisher:
Mary Ann Liebert Inc.
Journal:
Journal of computational biology : a journal of computational molecular cell biology
Volume:
6
Issue:
1
Pages:
91-112
Publication date:
1999
DOI:
EISSN:
1557-8666
ISSN:
1066-5277
URN:
uuid:304b1f77-a3e0-4f4f-9103-35ee5817f8c3
Source identifiers:
53971
Local pid:
pubs:53971

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