Cultural issues in assessing quality of life in cancer clinical trials.
Over the past decade, there has been significant progress made into the field of quality of life in cancer clinical trials. Many cancer clinical trials now include quality of life as a secondary end-point, but only a very small number of trials include quality of life as a primary end-point. This article reviews and discusses issues that arise when developing a quality of life instrument for use in international cancer clinical trials. We describe problems that arise when trying to establish ...Expand abstract
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