- Abstract:
-
In metabolic bone diseases, the alterations in fibrillar level bone-material quality affecting macroscopic mechanical competence are not well-understood quantitatively. Here, we quantify the fibrillar level deformation in cantilever bending in a mouse model for hereditary rickets (Hpr). Microfocus in-situ synchrotron small-angle X-ray scattering (SAXS) combined with cantilever bending was used to resolve nanoscale fibril strain in tensile- and compressive tissue regions separately, with quant...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.bone.2012.10.029
-
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- Journal:
- Bone
- Volume:
- 52
- Issue:
- 2
- Pages:
- 689-698
- Publication date:
- 2013-02-05
- DOI:
- EISSN:
-
1873-2763
- ISSN:
-
8756-3282
- URN:
-
uuid:30289edb-b5ab-48bc-9f97-cd54beb43c8a
- Source identifiers:
-
358285
- Local pid:
- pubs:358285
- Copyright date:
- 2013
Journal article
Symmetrically reduced stiffness and increased extensibility in compression and tension at the mineralized fibrillar level in rachitic bone.
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