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Functional compensation afforded by grafts of foetal neurones.

Abstract:

1. Adult neurones grafted to the adult nervous system show limited survival and growth potential. By contrast, certain foetal neurones of a defined age, when grafted to the damaged adult nervous system survive, and form a dense innervation of the host brain with morphologically defined synapses. Monamine containing neurones in the rat have these properties. In a number of model systems their ability to survive grafting to the adult brain has been demonstrated, the optimal conditions for their...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Progress in neuro-psychopharmacology and biological psychiatry
Volume:
13
Issue:
3-4
Pages:
453-467
Publication date:
1989-01-01
DOI:
EISSN:
1878-4216
ISSN:
0278-5846
URN:
uuid:30176a08-31c8-4905-9067-35a9bc1d4319
Source identifiers:
17618
Local pid:
pubs:17618
Language:
English
Keywords:

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