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Journal article

Interferon effects on osteoinduction.

Abstract:

Xenografts of human osteosarcoma growing in athymic mice are inhibited in growth rate by human interferon-alpha (IFN-alpha) treatment. In addition, differentiation of trabecular bone occurs external to the osteosarcomatous tissue and this is entirely dependent on IFN treatment. We have used species-specific anticollagens and antivimentin antibodies to determine the species origins of this trabecular bone. By using immunohistochemical procedures, it was found that this bone is host-derived. Th...

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Publication status:
Published

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Publisher copy:
10.3109/03008208909002414

Authors


Publisher:
Informa Healthcare
Journal:
Connective tissue research
Volume:
23
Issue:
2-3
Pages:
145-151
Publication date:
1989-01-01
DOI:
EISSN:
1607-8438
ISSN:
0300-8207
URN:
uuid:2ff5e15b-5de1-42e4-b5f1-8021d989088a
Source identifiers:
108510
Local pid:
pubs:108510

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