- Abstract:
-
Xenografts of human osteosarcoma growing in athymic mice are inhibited in growth rate by human interferon-alpha (IFN-alpha) treatment. In addition, differentiation of trabecular bone occurs external to the osteosarcomatous tissue and this is entirely dependent on IFN treatment. We have used species-specific anticollagens and antivimentin antibodies to determine the species origins of this trabecular bone. By using immunohistochemical procedures, it was found that this bone is host-derived. Th...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.3109/03008208909002414
-
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- Publisher:
- Informa Healthcare
- Journal:
- Connective tissue research
- Volume:
- 23
- Issue:
- 2-3
- Pages:
- 145-151
- Publication date:
- 1989-01-01
- DOI:
- EISSN:
-
1607-8438
- ISSN:
-
0300-8207
- URN:
-
uuid:2ff5e15b-5de1-42e4-b5f1-8021d989088a
- Source identifiers:
-
108510
- Local pid:
- pubs:108510
- Language:
- English
- Keywords:
- Copyright date:
- 1989
Journal article
Interferon effects on osteoinduction.
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