- Abstract:
-
Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a cell surface glycoprotein receptor expressed on a range of blood cells, including platelets, and on vascular endothelial cells. PECAM-1 possesses adhesive and signaling properties, the latter being mediated by immunoreceptor tyrosine-based inhibitory motifs present on the cytoplasmic tail of the protein. Recent studies in vitro have demonstrated that PECAM-1 signaling inhibits the aggregation of platelets. In the present study we ha...
Expand abstract - Publisher copy:
- 10.1182/blood-2005-04-1512
-
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- Journal:
- Blood
- Volume:
- 107
- Issue:
- 2
- Pages:
- 535-541
- Publication date:
- 2006-01-05
- DOI:
- EISSN:
-
1528-0020
- ISSN:
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0006-4971
- URN:
-
uuid:2fc81008-7f93-4c89-a269-aadd8ab0fd63
- Source identifiers:
-
244766
- Local pid:
- pubs:244766
- Copyright date:
- 2006
Journal article
Platelet PECAM-1 inhibits thrombus formation in vivo.
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