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Does peripheral neuroinflammation predict chronicity following whiplash injury? Protocol for a prospective cohort study

Abstract:

Introduction: Whiplash-associated disorder grade 2 (WAD2) is characterised by musculoskeletal pain/tenderness but no apparent nerve injury. However, studies have found clinical features indicative of neuropathy and neuropathic pain. These studies may indicate peripheral nerve inflammation, since preclinical neuritis models found mechanical sensitivity in inflamed, intact nociceptors. The primary aim of this study is to establish the contribution of peripheral neuroinf...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmjopen-2022-066021

Authors


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Role:
Author
ORCID:
0000-0003-2226-6531
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Name:
Wellcome Trust
Grant:
222101/Z/20/Z
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Name:
Medical Research Foundation
Grant:
MRF-160-0013-ELP-SCHM-C0842
Publisher:
BMJ Publishing
Journal:
BMJ open More from this journal
Volume:
12
Issue:
12
Article number:
e066021
Publication date:
2022-12-15
Acceptance date:
2022-11-21
DOI:
EISSN:
2044-6055
Pmid:
36521884

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