Journal article
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
- Abstract:
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The rarity of mutations in PALB2, CHEK2 and ATM make it difficult to estimate precisely associated cancer risks. Population-based family studies have provided evidence that at least some of these mutations are associated with breast cancer risk as high as those associated with rare BRCA2 mutations. We aimed to estimate the relative risks associated with specific rare variants in PALB2, CHEK2 and ATM via a multicentre case-control study.We genotyped 10 rare mutations using the custom iCOGS arr...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 454.7KB, Terms of use)
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- Publisher copy:
- 10.1136/jmedgenet-2016-103839
Authors
Bibliographic Details
- Publisher:
- BMJ Publishing Group
- Journal:
- Journal of Medical Genetics More from this journal
- Volume:
- 53
- Issue:
- 12
- Pages:
- 800-811
- Publication date:
- 2016-09-05
- Acceptance date:
- 2016-06-21
- DOI:
- EISSN:
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1468-6244
- ISSN:
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0022-2593
- Pmid:
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27595995
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:641722
- UUID:
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uuid:2fb80b0b-0cdc-4ab2-af3f-96adeda03118
- Local pid:
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pubs:641722
- Source identifiers:
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641722
- Deposit date:
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2016-10-05
Terms of use
- Copyright holder:
- Southey et al
- Copyright date:
- 2016
- Notes:
- This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
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