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Harnessing the Therapeutic Potential of Th17 Cells.

Abstract:

Th17 cells provide protective immunity to infections by fungi and extracellular bacteria as well as cancer but are also involved in chronic inflammation. The cells were first identified by their ability to produce interleukin 17A (IL-17A) and, subsequently, associated with chronic inflammation and autoimmunity. Th17 cells have some gene profile similarity with stem cells and can remain dormant in mucosal tissues for long periods. Indeed, recent studies suggest that functionally distinct subse...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1155/2015/205156

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, KIR
Role:
Author
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Publisher:
Hindawi Publishing Corporation Publisher's website
Journal:
Mediators of Inflammation Journal website
Volume:
2015
Pages:
205156
Chapter number:
ARTN 205156
Publication date:
2015-05-05
DOI:
EISSN:
1466-1861
ISSN:
0962-9351
URN:
uuid:2f82bb31-e207-4117-bcae-a0bfa2946c3e
Source identifiers:
528481
Local pid:
pubs:528481
Language:
English

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