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Journal article

TNFR-associated factor-2 (TRAF-2) in Alzheimer's disease.

Abstract:

Levels of tumor necrosis factor-alpha (TNF-alpha) are increased in the brain in Alzheimer's disease (AD). The TNF-alpha/TNF-R signaling pathways involve complex interactions between several proteins, including TNF-receptor-associated factor-2 (TRAF-2). We have examined the distribution and levels of TRAF-2 in AD and control brains and also whether single nucleotide polymorphisms (SNPs) in the TRAF-2 gene are associated with AD and influence TRAF-2 expression. Immunohistochemistry demonstrated...

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Publication status:
Published

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Authors


Chalmers, K More by this author
Cornish, A More by this author
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Journal:
Neurobiology of aging
Volume:
30
Issue:
7
Pages:
1052-1060
Publication date:
2009-07-05
DOI:
EISSN:
1558-1497
ISSN:
0197-4580
URN:
uuid:2f7f4e41-029b-41d3-9e12-8b46900cb59d
Source identifiers:
34074
Local pid:
pubs:34074

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