Thesis
Mathematical modelling of flow and nutrient transport in hollow fibre membrane bioreactors
- Abstract:
-
Hollow fibre membrane bioreactors comprise permeable tubes situated within a bioreactor chamber. Nutrients and growth factors flow through the fibre lumen, transporting across the porous membrane to external cells, while external flow removes residual nutrients and cellular waste. Given cellular sensitivity to their local microenvironment, mathematical modelling can be used to predict and optimise bioreactor performance.
In this thesis, we develop a series of continuum models descr...
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Authors
Contributors
+ Waters, S
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Mathematical Institute
- Sub department:
- Mathematical Institute
- Oxford college:
- St Anne's College
- Role:
- Supervisor
- ORCID:
- 0000-0001-5285-0523
+ Dalwadi, M
- Institution:
- University College London
- Role:
- Supervisor
- ORCID:
- 0000-0001-5017-2116
+ Ye, H
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Engineering Science
- Sub department:
- Institute of Biomedical Engineering
- Oxford college:
- Linacre College
- Role:
- Supervisor
- ORCID:
- 0000-0001-7613-6041
+ Mouthuy, P
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- NDORMS
- Sub department:
- NDORMS
- Oxford college:
- Linacre College
- Role:
- Supervisor
- ORCID:
- 0000-0003-1192-6362
+ Engineering and Physical Sciences Research Council
More from this funder
- Funder identifier:
- https://ror.org/001aqnf71
- Grant:
- EP/L016044/1
- Programme:
- EPSRC Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research Centre for Doctoral Training
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2024-04-04
Terms of use
- Copyright holder:
- Booth, G
- Copyright date:
- 2023
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