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Journal article

Localization of the synovial sarcoma t(X;18)(p11.2;q11.2) breakpoint by fluorescence in situ hybridization.

Abstract:

A high proportion of synovial sarcomas contain a chromosome translocation t(X;18)(p11.2;q11.2). We have previously used somatic cell hybrids derived from an established cell line, SS255, to map the X chromosome breakpoint to the interval flanked by the markers DXS14 and DXS146. In this study we have examined these hybrids with thirteen additional markers located at Xp11.3-Xcen, by Southern hybridization. Based on these results we have delimited the breakpoint as follows Xpter-DXS228-(UBE1-OAT...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/1.8.633

Authors


Knight, JC More by this author
Reeves, BR More by this author
Kearney, L More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Lehrach, H More by this author
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Journal:
Human molecular genetics
Volume:
1
Issue:
8
Pages:
633-637
Publication date:
1992-11-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:2f31bdd4-7610-4e8a-aa43-ddf45f7545a4
Source identifiers:
115681
Local pid:
pubs:115681

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