Journal article
Signaling inhibition with radiation in colorectal cancer: clinical trials.
- Abstract:
-
Ras has been shown to increase radiation resistance. Thus, upstream and downstream pathways from Ras could be targets for manipulation of radiosensitivity. Epidermal growth factor receptor (EGFR) expression and Akt phosphorylation are also associated with the response to radiation. A retrospective study evaluating EGFR and Akt in patients treated with multimodality therapy found a significant association between P-Akt and treatment failure. Moreover, these data are strengthened by in vitro st...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/s0093-7754(03)00126-x
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Bibliographic Details
- Journal:
- Seminars in oncology
- Volume:
- 30
- Issue:
- 3 Suppl 6
- Pages:
- 56-67
- Publication date:
- 2003-06-01
- DOI:
- EISSN:
-
1532-8708
- ISSN:
-
0093-7754
- Source identifiers:
-
118193
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:118193
- UUID:
-
uuid:2f2edfac-2079-4340-ab41-68259dec4e18
- Local pid:
- pubs:118193
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2003
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