Myofibroblast distribution in Dupuytren's cords: correlation with digital contracture.

Journal article

PURPOSE: Dupuytren's tissue has typically been described as being composed of myofibroblast-rich palmar nodules and relatively acellular tendon-like cords. We aimed to determine myofibroblast distribution (alpha-smooth muscle actin [alpha-SMA] positive cells) within Dupuytren's tissue and to correlate histologically defined alpha-SMA-positive nodules with digital contracture and recurrent disease. METHODS: One hundred and three digital Dupuytren's cords (72 fasciectomy, 31 dermofasciectomy) ...

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Authors: Verjee, L; Midwood, K; Davidson, D; Essex, D; Sandison, A

• Publication status: Published
• Journal: Journal of hand surgery
• Volume: 34
• Issue: 10
• Pages: 1785-1794
• Publication date: 2009-12-01
• DOI: 10.1016/j.jhsa.2009.08.005
• EISSN: 1531-6564
• ISSN: 0363-5023
• Language: English
• Keywords: Statistics as Topic; Female; Humans; Fascia; Fibroblasts; Recurrence; Metacarpophalangeal Joint; Postoperative Complications; Fingers; Myoblasts; Middle Aged; Tendons; Male; Dupuytren Contracture; Aged; Actins; Finger Joint; Adult; Aged, 80 and over