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Myofibroblast distribution in Dupuytren's cords: correlation with digital contracture.

Abstract:

PURPOSE: Dupuytren's tissue has typically been described as being composed of myofibroblast-rich palmar nodules and relatively acellular tendon-like cords. We aimed to determine myofibroblast distribution (alpha-smooth muscle actin [alpha-SMA] positive cells) within Dupuytren's tissue and to correlate histologically defined alpha-SMA-positive nodules with digital contracture and recurrent disease. METHODS: One hundred and three digital Dupuytren's cords (72 fasciectomy, 31 dermofasciectomy) ...

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Publication status:
Published

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Publisher copy:
10.1016/j.jhsa.2009.08.005

Authors


Verjee, LS More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Davidson, D More by this author
Sandison, A More by this author
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Journal:
The Journal of hand surgery
Volume:
34
Issue:
10
Pages:
1785-1794
Publication date:
2009-12-05
DOI:
EISSN:
1531-6564
ISSN:
0363-5023
URN:
uuid:2ee42595-1591-4763-9076-f962be654894
Source identifiers:
224788
Local pid:
pubs:224788

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