Journal article
A comparison of clofarabine with ara-C, each in combination with daunorubicin as induction treatment in older patients with acute myeloid leukaemia
- Abstract:
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The study was designed to compare clofarabine plus daunorubicin vs daunorubicin/ara-C in older patients with acute myeloid leukaemia (AML) or high-risk myelodysplastic syndrome (MDS). Eight hundred and six untreated patients in the UK NCRI AML16 trial with AML/high-risk MDS (median age, 67 years; range 56–84) and normal serum creatinine were randomised to two courses of induction chemotherapy with either daunorubicin/ara-C (DA) or daunorubicin/clofarabine (DClo). Patients were also included i...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 964.2KB)
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- Publisher copy:
- 10.1038/leu.2016.225
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Authors
Funding
Cancer Research UK
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Bibliographic Details
- Publisher:
- Springer Nature Publishing Group Publisher's website
- Journal:
- Leukemia Journal website
- Volume:
- 31
- Pages:
- 310-317
- Publication date:
- 2016-09-02
- Acceptance date:
- 2016-07-12
- DOI:
- EISSN:
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1476-5551
- ISSN:
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0887-6924
- Source identifiers:
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930220
Item Description
- Keywords:
- Pubs id:
-
pubs:930220
- UUID:
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uuid:2ed6a2bb-b6fb-42bd-917d-5fdce7327164
- Local pid:
- pubs:930220
- Deposit date:
- 2018-11-13
Terms of use
- Copyright holder:
- Burnett et al
- Copyright date:
- 2016
- Notes:
- © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License.
- Licence:
- CC Attribution (CC BY)
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