- Abstract:
-
Placental malaria caused by Plasmodium falciparum contributes to ~200,000 child deaths annually, mainly due to low birth weight (LBW). Parasitized erythrocyte sequestration and consequent inflammation in the placenta are common attributes of placental malaria. The precise molecular details of placental changes leading to LBW are still poorly understood. We hypothesized that placental malaria may disturb maternofetal exchange of vitamins, lipids, and hormones mediated by the multi-ligand (n ~ ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 968.8kb)
-
- Publisher copy:
- 10.1038/srep24508
-
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- Publisher:
- Nature Publishing Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 6
- Pages:
- Article 24508
- Publication date:
- 2016-04-13
- Acceptance date:
- 2016-03-30
- DOI:
- ISSN:
-
2045-2322
- Pubs id:
-
pubs:616974
- URN:
-
uri:2ec4ab54-197b-455d-8cdb-7aa4ea3ab6a4
- UUID:
-
uuid:2ec4ab54-197b-455d-8cdb-7aa4ea3ab6a4
- Local pid:
- pubs:616974
- Language:
- English
- Keywords:
- Copyright holder:
- Lybbert et al.
- Copyright date:
- 2016
- Notes:
-
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license,
users will need to obtain permission from the license holder to reproduce the material.
Journal article
Abundance of megalin and Dab2 is reduced in syncytiotrophoblast during placental malaria, which may contribute to low birth weight
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