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People of the British Isles: Preliminary analysis of genotypes and surnames in a UK-control population

Abstract:

There is a great deal of interest in a fine-scale population structure in the UK, both as a signature of historical immigration events and because of the effect population structure may have on disease association studies. Although population structure appears to have a minor impact on the current generation of genome-wide association studies, it is likely to have a significant part in the next generation of studies designed to search for rare variants. A powerful way of detecting such struct...

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Publisher copy:
10.1038/ejhg.2011.127

Authors


Boumertit, A More by this author
Davison, D More by this author
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Journal:
European Journal of Human Genetics
Volume:
20
Issue:
2
Pages:
203-210
Publication date:
2012-02-05
DOI:
EISSN:
1476-5438
ISSN:
1018-4813
URN:
uuid:2ebc7268-ee81-46f0-87a7-53dfdbb40713
Source identifiers:
254398
Local pid:
pubs:254398

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