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Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.

Abstract:

BACKGROUND: Despite improvements in the emergency treatment of myocardial infarction (MI), early mortality and morbidity remain high. The antiplatelet agent clopidogrel adds to the benefit of aspirin in acute coronary syndromes without ST-segment elevation, but its effects in patients with ST-elevation MI were unclear. METHODS: 45,852 patients admitted to 1250 hospitals within 24 h of suspected acute MI onset were randomly allocated clopidogrel 75 mg daily (n=22,961) or matching placebo (n=2...

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Publication status:
Published

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Journal:
Lancet
Volume:
366
Issue:
9497
Pages:
1607-1621
Publication date:
2005-11-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:2eb2f787-a9b4-44c7-ade8-52b1495d7263
Source identifiers:
33296
Local pid:
pubs:33296

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