Journal article
Synthesis and use of cell-permeant cyclic ADP-ribose.
- Abstract:
-
Cyclic ADP-ribose (cADPR) is a second messenger that acts on ryanodine receptors to mobilize Ca(2+). cADPR has a net negative charge at physiological pH making it not passively membrane permeant thereby requiring it to be injected, electroporated or loaded via liposomes. Such membrane impermeance of other charged intracellular messengers (including cyclic AMP, inositol 1,4,5-trisphosphate and nicotinic acid adenine dinucleotide phosphate) and fluorescent dyes (including fura-2 and fluorescein...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.bbrc.2012.01.025
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Authors
Bibliographic Details
- Journal:
- Biochemical and biophysical research communications
- Volume:
- 418
- Issue:
- 2
- Pages:
- 353-358
- Publication date:
- 2012-02-01
- DOI:
- EISSN:
-
1090-2104
- ISSN:
-
0006-291X
- Source identifiers:
-
246277
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:246277
- UUID:
-
uuid:2e70b7b1-a5fa-4e46-afd5-14c5c90d18c5
- Local pid:
- pubs:246277
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2012
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