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Journal article

Evolutionarily conserved human targets of adenosine to inosine RNA editing.

Abstract:

A-to-I RNA editing by ADARs is a post-transcriptional mechanism for expanding the proteomic repertoire. Genetic recoding by editing was so far observed for only a few mammalian RNAs that are predominantly expressed in nervous tissues. However, as these editing targets fail to explain the broad and severe phenotypes of ADAR1 knockout mice, additional targets for editing by ADARs were always expected. Using comparative genomics and expressed sequence analysis, we identified and experimentally v...

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Publication status:
Published online

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Publisher copy:
10.1093/nar/gki239

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Journal:
Nucleic acids research
Volume:
33
Issue:
4
Pages:
1162-1168
Publication date:
2005-01-05
DOI:
EISSN:
1362-4962
ISSN:
0305-1048
URN:
uuid:2e5dd80e-7541-4d0a-b567-2863c30667dd
Source identifiers:
334666
Local pid:
pubs:334666

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