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Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays.

Abstract:

Ankylosing Spondylitis (AS) is a common, inflammatory rheumatic disease, which primarily affects the axial skeleton and is associated with sacroiliitis, uveitis and enthesitis. Unlike other autoimmune rheumatic diseases, such as rheumatoid arthritis or systemic lupus erythematosus, autoantibodies have not yet been reported to be a feature of AS. We therefore wished to determine if plasma from patients with AS contained autoantibodies and if so, characterize and quantify this response in compa...

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Publisher copy:
10.1074/mcp.M900384-MCP200

Authors


Trudgian, D More by this author
Fischer, R More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, CCMP
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Journal:
Mol Cell Proteomics
Volume:
11
Issue:
2
Publication date:
2010-02-01
DOI:
EISSN:
1535-9484
ISSN:
1535-9476
URN:
uuid:2e4149e3-41c0-4791-8c18-bb56f3e39b2f
Source identifiers:
48463
Local pid:
pubs:48463
Language:
English

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