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Human papilloma virus E1-specific T cell immune response is associated with the prognosis of cervical cancer patients with squamous cell carcinoma

Abstract:
Background Cervical cancer is attributable to human papilloma virus (HPV) infection in the majority cases. E1, an HPV derived-protein, plays an important role in the initiation and development of cervical cancer. Our study aims to investigate the HPV E1-specific T cell response in patients with cervical squamous cell carcinoma (CSCC). Methods A total of 66 CSCC patients with FIGO stage IIB-IIIB and 60 healthy controls were enrolled. Enzyme-Linked ImmunoSpot ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s13027-018-0206-5

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
Weatherall Insti. of Molecular Medicine
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
Weatherall Insti. of Molecular Medicine
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John Fell Fund More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Infectious Agents and Cancer Journal website
Volume:
13
Issue:
1
Pages:
Article: 35
Publication date:
2018-11-16
Acceptance date:
2018-10-26
DOI:
ISSN:
1750-9378
Pubs id:
pubs:948885
URN:
uri:2e370491-da89-44c7-a79a-20ffb75022b0
UUID:
uuid:2e370491-da89-44c7-a79a-20ffb75022b0
Local pid:
pubs:948885

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