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Tracking the antigenic evolution of Foot-and-Mouth Disease virus

Abstract:

Quantifying and predicting the antigenic characteristics of a virus is something of a holy grail for infectious disease research because of its central importance to the emergence of new strains, the severity of outbreaks, and vaccine selection. However, these characteristics are defined by a complex interplay of viral and host factors so that phylogenetic measures of viral similarity are often poorly correlated to antigenic relationships. Here, we generate antigenic phylogenies that track th...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0159360

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Role:
Author
ORCID:
0000-0003-2589-8091
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Role:
Author
ORCID:
0000-0002-4456-2270
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
11
Issue:
7
Pages:
e0159360
Publication date:
2016-07-22
Acceptance date:
2016-07-02
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Pubs id:
pubs:635586
URN:
uri:2e314771-8aef-41aa-9785-002c87f008de
UUID:
uuid:2e314771-8aef-41aa-9785-002c87f008de
Local pid:
pubs:635586

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