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Schizophrenia delays and alters maturation of the brain in adolescence.

Abstract:

Early-onset schizophrenia appears to be clinically more severe than the adult-onset form of the disease. In a previous study, we showed that anatomically related grey and white matter abnormalities found in adolescents patients were larger and more widespread than what had been reported in the literature on adult schizophrenia. Particularly, we found novel structural abnormalities in the primary sensorimotor and premotor systems. Here, we tested alternative hypotheses: either this striking se...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awp126

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Brain : a journal of neurology
Volume:
132
Issue:
Pt 9
Pages:
2437-2448
Publication date:
2009-09-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:2e1114ac-83a8-423e-b2f2-ac9e234b8945
Source identifiers:
116222
Local pid:
pubs:116222

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