Journal article
Increased expression of the 5-HT transporter confers a low-anxiety phenotype linked to decreased 5-HT transmission.
- Abstract:
-
A commonly occurring polymorphic variant of the human 5-hydroxytryptamine (5-HT) transporter (5-HTT) gene that increases 5-HTT expression has been associated with reduced anxiety levels in human volunteer and patient populations. However, it is not known whether this linkage between genotype and anxiety relates to variation in 5-HTT expression and consequent changes in 5-HT transmission. Here we test this hypothesis by measuring the neurochemical and behavioral characteristics of a mouse gene...
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- Publication status:
- Published
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- Publisher copy:
- 10.1523/jneurosci.5356-05.2006
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Bibliographic Details
- Journal:
- Journal of neuroscience : the official journal of the Society for Neuroscience
- Volume:
- 26
- Issue:
- 35
- Pages:
- 8955-8964
- Publication date:
- 2006-08-01
- DOI:
- EISSN:
-
1529-2401
- ISSN:
-
0270-6474
- Source identifiers:
-
4927
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:4927
- UUID:
-
uuid:2df04c05-3637-44f7-84f1-4a49920597d9
- Local pid:
- pubs:4927
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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