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The fate of implanted autologous chondrocytes in regenerated articular cartilage.

Abstract:

Autologous chondrocyte implantation (ACI) is used to treat some articular cartilage defects. However, the fate of the cultured chondrocytes after in-vivo transplantation and their role in cartilage regeneration remains unclear. To monitor the survival and fate of such cells in vivo, the chondrocytes were labelled with a lipophilic dye and the resultant regenerated tissue in dogs examined. It was found that, 4 weeks after implantation, the osteochondral defects were filled with regenerative ti...

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Publisher copy:
10.1243/09544119jeim202

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Journal:
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Volume:
221
Issue:
5
Pages:
461-465
Publication date:
2007-07-05
DOI:
EISSN:
2041-3033
ISSN:
0954-4119
URN:
uuid:2dd153d3-5d43-4e7b-9b46-607346ff24f7
Source identifiers:
108340
Local pid:
pubs:108340

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