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Journal article

Presentation of antigenic peptides by products of the major histocompatibility complex.

Abstract:

Molecules encoded by the major histocompatibility complex (MHC) are polymorphic integral membrane proteins adapted to the presentation of peptide fragments of foreign antigens to antigen-specific T-cells. The diversity of infectious agents to which an immune response must be mounted poses a unique problem for receptor-ligand interactions; how can proteins whose polymorphism is necessarily limited bind an array of peptides almost infinite in its complexity? Both MHC class I and class II determ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Journal of peptide science : an official publication of the European Peptide Society
Volume:
4
Issue:
3
Pages:
182-194
Publication date:
1998-05-05
DOI:
EISSN:
1099-1387
ISSN:
1075-2617
URN:
uuid:2db1bcff-d44b-423d-9d99-e5d16ecc78ce
Source identifiers:
21274
Local pid:
pubs:21274

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