- Abstract:
- The interaction of immunoglobulin E and otherwise harmless antigens (allergens) leads in sensitized individuals through effector cell activation to the immediate induction of a cascade of inflammatory reactions, the hallmark of type I allergy. Recently, the molecular and structural characterization of allergens, specific IgE antibodies and their epitopes has made rapid progress. Here we discuss active and passive strategies for therapy of type I allergy, which are based on interfering with the IgE-allergen interaction.
- Publication status:
- Published
- Publisher copy:
- 10.1159/000023942
-
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- Journal:
- International archives of allergy and immunology
- Volume:
- 116
- Issue:
- 3
- Pages:
- 167-176
- Publication date:
- 1998-07-05
- DOI:
- EISSN:
-
1423-0097
- ISSN:
-
1018-2438
- URN:
-
uuid:2da95989-65d1-4d85-aed5-847c35452ce9
- Source identifiers:
-
69750
- Local pid:
- pubs:69750
- Language:
- English
- Keywords:
- Copyright date:
- 1998
Journal article
The immunoglobulin E-allergen interaction: a target for therapy of type I allergic diseases.
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