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A comparison of protocols used to generate insulin-producing cell clusters from mouse embryonic stem cells.

Abstract:

Embryonic stem cells (ESCs) have the capacity to generate a panoply of tissue types and may therefore provide an alternative source of tissue in regenerative medicine to treat potentially debilitating conditions like Type 1 diabetes mellitus. However, the ability of mouse ESCs to generate insulin-producing cell clusters (IPCCs) remains highly contentious. In an attempt to clarify this issue, three protocols for the ESC-based generation of IPCCs (referred to as Blyszczuk, Hori, and Lumelsky pr...

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Publication status:
Published

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Publisher copy:
10.1634/stemcells.2007-0762

Authors


Higashi, Y More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Journal:
Stem cells (Dayton, Ohio)
Volume:
26
Issue:
5
Pages:
1128-1137
Publication date:
2008-05-05
DOI:
EISSN:
1549-4918
ISSN:
1066-5099
URN:
uuid:2d99ddfe-26af-4b98-93e3-a78943b0d4fc
Source identifiers:
135977
Local pid:
pubs:135977

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