Unity from diversity: the evidential use of anecdotal reports of adverse drug reactions and interactions.

Journal article

Anecdotal case reports contribute about one-third of the published literature on adverse drug reactions and interactions, but are regarded as providing poor-quality evidence. However, they can occasionally provide proof of cause and effect, and there are many other reasons for publishing them. Because an anecdote is a narrative, narratological paradigms from literature, art, and music can show how we can make evidential use of anecdotes. Useful paradigms are the dramatic unities (of time, pla...

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Authors: Aronson, J

• Publication status: Published
• Journal: Journal of evaluation in clinical practice
• Volume: 11
• Issue: 2
• Pages: 195-208
• Publication date: 2005-04-01
• DOI: 10.1111/j.1365-2753.2005.00527.x
• EISSN: 1365-2753
• ISSN: 1356-1294
• Language: English
• Keywords: Catalogs, Drug; Humans; Narration; Anecdotes as Topic; Evidence-Based Medicine; Drug Interactions; Classification; Drug Therapy