To rationalize the experimental results observed in the asymmetric conjugate addition of alkenylboronates to enones catalyzed by binaphthols and shed light into the factors controlling the rate, the selectivity, and the substituent effects of this process, a theoretical DFT study has been performed. The calculations suggest the catalytic cycle is finely balanced. Reversible exchange of methoxy ligands gives rise to the binaphthol-derived alkenylboronate, which is highly Lewis acidic and stron...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Theoretical study of the asymmetric conjugate alkenylation of enones catalyzed by binaphthols.
If you are the owner of this record, you can report an update to it here: Report update to this record