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Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy.

Abstract:

A crystallization screening process is presented that was developed for a small academic laboratory. Its underlying concept is to combine sparse-matrix screening with systematic screening in a minimum number of crystallization conditions. The sparse-matrix screen is the cherry-picked combination of conditions from the Joint Center for Structural Genomics (JCSG) extended using conditions from other screens. Its aim is to maximize the coverage of crystallization parameter space with no redundan...

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Publication status:
Published

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Publisher copy:
10.1107/s0907444905024984

Authors


Walter, TS More by this author
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Journal:
Acta crystallographica. Section D, Biological crystallography
Volume:
61
Issue:
Pt 10
Pages:
1426-1431
Publication date:
2005-10-05
DOI:
EISSN:
1399-0047
ISSN:
0907-4449
URN:
uuid:2d6ae622-66ad-4bb8-baac-1a3a43121656
Source identifiers:
26352
Local pid:
pubs:26352

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