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Wnt disruption in colorectal polyps - the traditional serrated adenoma enters the fray

Abstract:

The adenoma-carcinoma sequence describes the development of colorectal carcinoma (CRC) from benign colorectal precursor lesions. Molecular classification of established CRC has demonstrated considerable disease heterogeneity; however, as an emerging cancer frequently outgrows and destroys the initial precursor lesion, CRC molecular taxonomy can only be partially reconciled with histologically classified polyps. Thus, the molecular pathogenesis of some colorectal polyp types, including the tra...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/path.4741

Authors


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Department:
Magdalen College
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Funding agency for:
Leedham, S
Publisher:
Wiley Publisher's website
Journal:
Journal of Pathology Journal website
Volume:
239
Issue:
4
Pages:
387-390
Publication date:
2016-07-06
Acceptance date:
2016-05-12
DOI:
EISSN:
1096-9896
ISSN:
0022-3417
Pubs id:
pubs:637598
URN:
uri:2d35278d-ac4b-45a0-8d26-48c06a1e455a
UUID:
2d35278d-ac4b-45a0-8d26-48c06a1e455a
Local pid:
pubs:637598

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