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Effects of atorvastatin on endothelial function and the expression of proinflammatory cytokines and adhesion molecules in young subjects with successfully repaired coarctation of aorta.

Abstract:

OBJECTIVE: To investigate the effects of atorvastatin on endothelial function and low-grade systemic inflammation in subjects with successful surgery for aortic coarctation repair (SCR). DESIGN: Open-label study. SETTING: Outpatients visiting the adult congenital heart disease department of our hospital. PATIENTS: 34 young people with SCR. INTERVENTIONS: Patients with SCR received atorvastatin 10 mg/day (n=17) or no treatment (n=17) for 4 weeks. At baseline and at 4 weeks, endothelial functi...

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Authors


Tousoulis, D More by this author
Antonopoulos, AS More by this author
Antoniades, C More by this author
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Journal:
Heart (British Cardiac Society)
Volume:
98
Issue:
4
Pages:
325-329
Publication date:
2012-02-05
DOI:
EISSN:
1468-201X
ISSN:
1355-6037
URN:
uuid:2d3522fe-c02e-4acd-87dd-7691638e5f55
Source identifiers:
223320
Local pid:
pubs:223320

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