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Synthesis of a hemifluorinated amphiphile designed for self-assembly and two-dimensional crystallization of membrane protein

Abstract:
The work reported herein deals with the synthesis and the preliminary physical-chemical analysis of new hemifluorinated surfactant made up of one fluorinated chain linked to a tricarboxylic acid polar head which is able to complex a Ni atom and should favor the two-dimensional crystallization of membrane proteins. Such a compound forms a Langmuir film which is a fluid at 20 °C and not perturbed by the presence of hydrocarbon detergent in aqueous solution. © 2008 Elsevier Ltd. All rights reserved.
Publication status:
Published

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Authors


Dauvergne, J More by this author
Polidori, A More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Journal:
TETRAHEDRON LETTERS
Volume:
49
Issue:
14
Pages:
2247-2250
Publication date:
2008-03-31
DOI:
ISSN:
0040-4039
URN:
uuid:2d10d8b9-e0d2-4d90-913b-c7072b8d8ebf
Source identifiers:
100788
Local pid:
pubs:100788

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