Synthesis of a hemifluorinated amphiphile designed for self-assembly and two-dimensional crystallization of membrane protein
- The work reported herein deals with the synthesis and the preliminary physical-chemical analysis of new hemifluorinated surfactant made up of one fluorinated chain linked to a tricarboxylic acid polar head which is able to complex a Ni atom and should favor the two-dimensional crystallization of membrane proteins. Such a compound forms a Langmuir film which is a fluid at 20 °C and not perturbed by the presence of hydrocarbon detergent in aqueous solution. © 2008 Elsevier Ltd. All rights reserved.
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