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Dissociable effects of acute antidepressant drug administration on subjective and emotional processing measures in healthy volunteers.

Abstract:

BACKGROUND: We have previously shown that single doses of serotonin-selective and noradrenaline-selective antidepressant agents produce positive biases in measures of emotional processing in healthy volunteers. The aim of the present study was to confirm and extend this finding by studying the effects of a single dose of the selective serotonin and noradrenaline re-uptake inhibitor, duloxetine. MATERIALS AND METHODS: Healthy volunteers were randomly allocated to double-blind administration of...

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Publication status:
Published

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Publisher copy:
10.1007/s00213-007-1058-7

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Heinzen, J More by this author
O'Sullivan, U More by this author
Journal:
Psychopharmacology
Volume:
199
Issue:
4
Pages:
495-502
Publication date:
2008-09-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:2cec479a-cf20-42fc-87cb-2cce5a35e497
Source identifiers:
139388
Local pid:
pubs:139388

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