Journal article
CSF chitinases before and after symptom onset in amyotrophic lateral sclerosis
- Abstract:
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Objective To evaluate the CSF levels of chitinase proteins during the presymptomatic and early symptomatic phases of amyotrophic lateral sclerosis (ALS).
Methods CSF samples were obtained from 16 controls, 55 individuals at‐risk for ALS (including 18 carrying a mutation in C9ORF72 , 33 in SOD1 ), 12 ALS patients, and 7 phenoconverters (individuals diagnosed with ALS during follow‐up). At‐risk individuals and phenoconverters were enrolled through th...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 2.2MB, Terms of use)
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- Publisher copy:
- 10.1002/acn3.51114
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Bibliographic Details
- Publisher:
- Wiley
- Journal:
- Annals of Clinical and Translational Neurology More from this journal
- Volume:
- 7
- Issue:
- 8
- Pages:
- 1296-1306
- Publication date:
- 2020-07-14
- Acceptance date:
- 2020-06-04
- DOI:
- EISSN:
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2328-9503
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1109331
- Local pid:
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pubs:1109331
- Deposit date:
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2020-06-05
Terms of use
- Copyright holder:
- Gray et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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