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Deletion of the GluA1 AMPA receptor subunit alters the expression of short-term memory.

Abstract:

Deletion of the GluA1 AMPA receptor subunit selectively impairs short-term memory for spatial locations. We further investigated this deficit by examining memory for discrete nonspatial visual stimuli in an operant chamber. Unconditioned suppression of magazine responding to visual stimuli was measured in wild-type and GluA1 knockout mice. Wild-type mice showed less suppression to a stimulus that had been presented recently than to a stimulus that had not. GluA1 knockout mice, however, showed...

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Publication status:
Published

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Publisher copy:
10.1101/lm.2014911

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Learning and memory (Cold Spring Harbor, N.Y.)
Volume:
18
Issue:
3
Pages:
128-131
Publication date:
2011-03-05
DOI:
EISSN:
1549-5485
ISSN:
1072-0502
URN:
uuid:2cda87df-506b-4ab5-b114-4d2851e48d66
Source identifiers:
118075
Local pid:
pubs:118075

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