Journal article
p21WAF1/CIP1 and MDM2 expression in non-Hodgkin's lymphoma and their relationship to p53 status: a p53+, MDM2-, p21-immunophenotype associated with missense p53 mutations.
- Abstract:
-
p53 is a tumour suppressor gene which is often found to be inactivated in most types of human cancer. p53 is a transcription factor, the inactivation of which may lead to significant variations in the levels of p53 downstream proteins, such as p21WAF1/CIP1 and MDM2. In view of the significance of p21WAF1/CIP1 and MDM2 as wild-type (wt) p53 targets, this study was undertaken to monitor the varying expression of these proteins in non-Hodgkin's lymphomas (NHLs) in relation to p53 gene status. A ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/(sici)1096-9896(199701)181:1<51::aid-path689>3.0.co;2-n
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Bibliographic Details
- Journal:
- Journal of pathology
- Volume:
- 181
- Issue:
- 1
- Pages:
- 51-61
- Publication date:
- 1997-01-01
- DOI:
- EISSN:
-
1096-9896
- ISSN:
-
0022-3417
- Source identifiers:
-
486718
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:486718
- UUID:
-
uuid:2c64f7b2-a155-4b15-bb05-eb791707aecf
- Local pid:
- pubs:486718
- Deposit date:
- 2014-10-23
Terms of use
- Copyright date:
- 1997
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