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Journal article

Cholesteryl ester transfer protein inhibition for preventing cardiovascular events: JACC review topic of the week

Abstract:

Cholesteryl ester transfer protein (CETP) facilitates exchange of triglycerides and cholesteryl ester between high-density lipoprotein (HDL) and apolipoprotein B100–containing lipoproteins. Evidence from genetic studies that variants in the CETP gene were associated with higher blood HDL cholesterol, lower low-density lipoprotein cholesterol, and lower risk of coronary heart disease suggested that pharmacological inhibition of CETP may be beneficial. To date, 4 CETP inhibitors have entered ph...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.jacc.2018.10.072

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0003-3139-1836
Publisher:
Elsevier Publisher's website
Journal:
Journal of the American College of Cardiology Journal website
Volume:
73
Issue:
4
Pages:
477-487
Publication date:
2019-01-28
Acceptance date:
2018-10-29
DOI:
ISSN:
0735-1097
Pubs id:
pubs:935380
URN:
uri:2c5fd2fd-d566-498c-b9da-aa3cd855c99f
UUID:
uuid:2c5fd2fd-d566-498c-b9da-aa3cd855c99f
Local pid:
pubs:935380

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