- Abstract:
-
Cholesteryl ester transfer protein (CETP) facilitates exchange of triglycerides and cholesteryl ester between high-density lipoprotein (HDL) and apolipoprotein B100–containing lipoproteins. Evidence from genetic studies that variants in the CETP gene were associated with higher blood HDL cholesterol, lower low-density lipoprotein cholesterol, and lower risk of coronary heart disease suggested that pharmacological inhibition of CETP may be beneficial. To date, 4 CETP inhibitors have entered ph...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(docx, 21.2KB)
-
(pdf, 758.6KB)
-
- Publisher copy:
- 10.1016/j.jacc.2018.10.072
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of the American College of Cardiology Journal website
- Volume:
- 73
- Issue:
- 4
- Pages:
- 477-487
- Publication date:
- 2019-01-28
- Acceptance date:
- 2018-10-29
- DOI:
- ISSN:
-
0735-1097
- Pubs id:
-
pubs:935380
- URN:
-
uri:2c5fd2fd-d566-498c-b9da-aa3cd855c99f
- UUID:
-
uuid:2c5fd2fd-d566-498c-b9da-aa3cd855c99f
- Local pid:
- pubs:935380
- Copyright holder:
- Armitage et al.
- Copyright date:
- 2019
- Notes:
- Copyright © 2019 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Journal article
Cholesteryl ester transfer protein inhibition for preventing cardiovascular events: JACC review topic of the week
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