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Journal article

Interleukin-4 induced down-regulation of skin homing receptor expression by human viral-specific CD8 T cells may contribute to atopic risk of cutaneous infection.

Abstract:

Factors controlling the expression of cutaneous lymphocyte-associated antigen (CLA) by T cells are poorly understood, but data from murine and human CD4(+) T cell systems have suggested that cytokines play an important role. However, there are no data examining the influence of cytokines on the expression of CLA by human antigen-specific CD8(+) T cells. Peripheral blood mononuclear cells (PBMC) were isolated from 10 HLA-A*0201-positive healthy individuals. Using HLA-peptide tetrameric complex...

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Publication status:
Published

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Authors


Seneviratne, SL More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Bailey, AS More by this author
Samuel, RV More by this author
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Journal:
Clinical and experimental immunology
Volume:
141
Issue:
1
Pages:
107-115
Publication date:
2005-07-05
DOI:
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:2c529400-205e-4591-b564-07f353d52c9e
Source identifiers:
6779
Local pid:
pubs:6779

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