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Journal article

Lack of annexin 1 results in an increase in corticotroph number in male but not female mice.

Abstract:

Annexin 1 (ANXA1) is a member of the annexin family of phospholipid- and calcium-binding proteins with a well demonstrated role in early delayed (30 min to 3 h) inhibitory feedback of glucocorticoids in the pituitary. We have examined corticotrophs in wild-type and ANXA1 knockout mice to determine the effects of lack of ANXA1 in male and female animals. Anterior pituitary tissue from ANXA1 wild-type, heterozygote and null mice was fixed and examined (i) by confocal immunocytochemistry to dete...

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Publication status:
Published

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Journal:
Journal of neuroendocrinology
Volume:
18
Issue:
11
Pages:
835-846
Publication date:
2006-11-05
DOI:
EISSN:
1365-2826
ISSN:
0953-8194
URN:
uuid:2c2c3fc6-b45b-45ae-b274-014f85f65a52
Source identifiers:
114203
Local pid:
pubs:114203

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