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Can one learn history from the allelic spectrum?

Abstract:
It is well known that the neutral allelic frequency spectrum of a population is affected by the history of population size. A number of authors have used this fact to infer history given observed allele frequency data. We ask whether perfect information concerning the spectrum allows precise recovery of the history, and with an explicit example show that the answer is in the negative. This implies some limitations on how informative allelic spectra can be.
Publication status:
Published

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Publisher copy:
10.1016/j.tpb.2008.01.001

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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics, Clinical Medicine
Role:
Author
Journal:
Theoretical population biology
Volume:
73
Issue:
3
Pages:
342-348
Publication date:
2008-05-05
DOI:
EISSN:
1096-0325
ISSN:
0040-5809
URN:
uuid:2c213c35-6655-4123-92b2-4b18be60b490
Source identifiers:
103189
Local pid:
pubs:103189

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