Journal article
Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis.
- Abstract:
-
CONTEXT: The adipokine adiponectin has insulin-sensitizing, antiatherogenic, and antiinflammatory properties. Mouse and human adiponectin receptor-1 and -2 have been cloned, both of which are expressed in various tissues and mediate effects of globular and full-length adiponectin. Whether adiponectin affects insulin secretion and beta-cell apoptosis and whether plasma adiponectin is associated with beta-cell function in humans is under investigation. DESIGN AND METHODS: In human islets from m...
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- Publication status:
- Published
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- Publisher copy:
- 10.1210/jc.2005-0467
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Authors
Bibliographic Details
- Journal:
- Journal of clinical endocrinology and metabolism
- Volume:
- 90
- Issue:
- 12
- Pages:
- 6707-6713
- Publication date:
- 2005-12-01
- DOI:
- EISSN:
-
1945-7197
- ISSN:
-
0021-972X
- Source identifiers:
-
266143
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:266143
- UUID:
-
uuid:2bed1e25-9f4f-4186-b1b2-ff20f046597a
- Local pid:
- pubs:266143
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2005
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