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Hailey-Hailey disease: a widespread abnormality of cell adhesion.

Abstract:

Suction has been used to investigate cell adhesion in clinically normal skin in Hailey-Hailey disease. We have demonstrated that there is a widespread subclinical abnormality in keratinocyte adhesion in this disease. There may be a synthesis of functionally deficient adhesion junctions, increased breakdown of adhesion junctions or abnormalities in other adhesion proteins in the epidermis in Hailey-Hailey disease. The findings contrast with those in Darier's disease in which abnormal cell adhe...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
The British journal of dermatology
Volume:
124
Issue:
4
Pages:
329-332
Publication date:
1991-04-05
DOI:
EISSN:
1365-2133
ISSN:
0007-0963
URN:
uuid:2bac5679-d6df-4ac9-adee-2ede11fb3c74
Source identifiers:
30253
Local pid:
pubs:30253

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